Hepatoprotective activity of Abutilon indicum on experimental liver damage in rats

被引：69
|
作者：
Porchezhian, E
Ansari, SH
机构：
[1] Dabur Res Fdn, Ghaziabad 201010, UP, India
[2] Hamdard Univ, Fac Pharm, Dept Phyotchem, New Delhi 110062, India
来源：
PHYTOMEDICINE | 2005年 / 12卷 / 1-2期
关键词：
Abutilon indicum; carbon tetrachloride; paracetamol;
D O I：
10.1016/j.phymed.2003.09.009
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The aqueous extract of Abutilon indicum was tested for hepatoprotective activity against carbon tetrachloride- and paracetamol-induced hepatotoxicities in rats. A. indicum exhibited significant hepatoprotective activity by reducing carbon tetrachloride- and paracetamol-induced change in bio-chemical parameters that was evident by enzymatic examination. The plant extract may interfere with free-radical formation, which may conclude in hepatoprotective action. Acute toxicity studies revealed that the LD50 value is more than the dose of 4 g/kg body wt. (C) 2004 Elsevier GmbH. All rights reserved.
引用
收藏
页码：62 / 64
页数：3
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