Functional changes of fetal muscle acetylcholine receptor during mouse development

被引:0
|
作者
Grassi, F [1 ]
Eusebi, F
机构
[1] Univ Rome La Sapienza, Ist Pasteur, Fdn Cenci Bolognetti, Rome, Italy
[2] Univ Rome La Sapienza, Dipartimento Med Sperimentale & Patol, Rome, Italy
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中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
In developing muscles in vivo and in vitro, the acetylcholine receptor gamma-subunit exists in two splice variants, conferring different single-channel open durations (tau(op)) to reconstituted receptors. In mouse muscles, tau(op) changes around birth possibly as receptors incorporate either variant of gamma-subunit. This might be relevant to the concomitant maturation of muscle innervation.
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页码:247 / 251
页数:5
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