Metal-Organic Frameworks and Their Composites Towards Biomedical Applications

被引：24
|
作者：
Ma, Yana [1 ,2 ]
Qu, Xianglong [3 ]
Liu, Cui [1 ,2 ]
Xu, Qiuran [4 ,5 ]
Tu, Kangsheng [3 ]
机构：
[1] Xi An Jiao Tong Univ, Sch Basic Med Sci, Xian Key Lab Immune Related Dis, Xian, Peoples R China
[2] Xi An Jiao Tong Univ, Key Lab Environm & Genes Related Dis, Minist Educ, Xian, Peoples R China
[3] Xi An Jiao Tong Univ, Dept Hepatobiliary Surg, Affiliated Hosp 1, Xian, Peoples R China
[4] Hangzhou Med Coll, Lab Tumor Mol Diag & Individualized Med Zhejiang, Zhejiang Prov Peoples Hosp, Affiliated Peoples Hosp, Hangzhou, Peoples R China
[5] Res Ctr Diag & Treatment Technol Hepatocellular C, Hangzhou, Peoples R China
来源：
FRONTIERS IN MOLECULAR BIOSCIENCES | 2021年 / 8卷
基金：
中国国家自然科学基金;
关键词：
metal-organic frameworks; nanomedicine; therapeutics; imaging; theranostics; sensors; POST-SYNTHETIC MODIFICATION; DRUG-DELIVERY; ANTICANCER DRUG; PHOTODYNAMIC THERAPY; MULTIDRUG-RESISTANCE; CANCER; NANOPARTICLES; MEMBRANE; RELEASE; GLUCOSE;
D O I：
10.3389/fmolb.2021.805228
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Owing to their unique features, including high cargo loading, biodegradability, and tailorability, metal-organic frameworks (MOFs) and their composites have attracted increasing attention in various fields. In this review, application strategies of MOFs and their composites in nanomedicine with emphasis on their functions are presented, from drug delivery, therapeutic agents for different diseases, and imaging contrast agents to sensor nanoreactors. Applications of MOF derivatives in nanomedicine are also introduced. Besides, we summarize different functionalities related to MOFs, which include targeting strategy, biomimetic modification, responsive moieties, and other functional decorations. Finally, challenges and prospects are highlighted about MOFs in future applications.
引用
收藏
页数：24
相关论文
共 50 条
  • [1] Metal-Organic Frameworks for Biomedical Applications
    Yang, Jie
    Yang, Ying-Wei
    [J]. SMALL, 2020, 16 (10)
  • [2] Metal-organic frameworks for pharmaceutical and biomedical applications
    Rezaee, Tooba
    Fazel-Zarandi, Reihaneh
    Karimi, Afsaneh
    Ensafi, Ali A.
    [J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2022, 221
  • [3] Metal-organic frameworks for biomedical applications: A review
    Hefayathullah, Mohamed
    Singh, Smita
    Ganesan, Vellaichamy
    Maduraiveeran, Govindhan
    [J]. ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2024, 331
  • [4] Metal-Organic Frameworks and Their Composites for Environmental Applications
    Zhang, Qian
    Yang, Hui
    Zhou, Ting
    Chen, Xudong
    Li, Wenting
    Pang, Huan
    [J]. ADVANCED SCIENCE, 2022, 9 (32)
  • [5] Antibacterial applications of metal-organic frameworks and their composites
    Shen, Mofei
    Forghani, Fereidoun
    Kong, Xueqian
    Liu, Donghong
    Ye, Xingqian
    Chen, Shiguo
    Ding, Tian
    [J]. COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, 2020, 19 (04): : 1397 - 1419
  • [6] Aqueous preparation of metal-organic frameworks for biomedical applications
    Morley, Emily
    Mangun, McKenzie
    Jamboretz, John
    Malloy, Kathryn
    Allen, Necoline
    Pak, Joshua
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 255
  • [7] Green metal-organic frameworks (MOFs) for biomedical applications
    Rabiee, Navid
    Atarod, Monireh
    Tavakolizadeh, Maryam
    Asgari, Shadi
    Rezaei, Mohsen
    Akhavan, Omid
    Pourjavadi, Ali
    Jouyandeh, Maryam
    Lima, Eder C.
    Mashhadzadeh, Amin Hamed
    Ehsani, Ali
    Ahmadi, Sepideh
    Saeb, Mohammad Reza
    [J]. MICROPOROUS AND MESOPOROUS MATERIALS, 2022, 335
  • [8] Opportunities and Challenges in Biomedical Applications of Metal-Organic Frameworks
    Salehipour, Masoud
    Rezaei, Shahla
    Rezaei, Mahsa
    Yazdani, Mahsa
    Mogharabi-Manzari, Mehdi
    [J]. JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, 2021, 31 (12) : 4443 - 4462
  • [9] Biomedical Applications of Metal-Organic Frameworks at the Subcellular Level
    Xue, Jueyi
    Liu, Jian
    Yong, Joel
    Liang, Kang
    [J]. ADVANCED NANOBIOMED RESEARCH, 2021, 1 (09):
  • [10] Metal-Organic Frameworks and Their Composites: Synthesis and Electrochemical Applications
    Yi, Fei-Yan
    Zhang, Rui
    Wang, Hailong
    Chen, Li-Feng
    Han, Lei
    Jiang, Hai-Long
    Xu, Qiang
    [J]. SMALL METHODS, 2017, 1 (11):
12345