Noncardiac chest pain

被引：46

作者：

Fass, Ronnie ^{[1
]}

Navarro-Rodriguez, Tomas ^{[1
]}

机构：

[1] Univ Arizona, So Arizona VA Hlth Car Syst, Dept Med, Neuroenter Clin Res Grp, Tucson, AZ 85723 USA

来源：

JOURNAL OF CLINICAL GASTROENTEROLOGY | 2008年 / 42卷 / 05期

关键词：

gastroesophageal reflux disease; noncardiac chest pain; nonspecific esophageal motility disorder; lower esophageal sphincter;

D O I：

10.1097/MCG.0b013e3181684c6b

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Noncardiac chest pain (NCCP) affects approximately 1 quarter of the adult population in the United States. The pathophysiology of the disorder remains to be fully elucidated. Identified underlying mechanisms for esophageal pain include gastroesophageal reflux disease (GERD), esophageal dysmotility, and visceral hypersensitivity. Aggressive antireflux treatment has been the main therapeutic strategy for GERD-related NCCP. NCCP patients with or without spastic esophageal motor disorders are responsive to pain modulators. The value of botulinum toxin injection, endoscopic treatment for GERD, and antireflux surgery in alleviating NCCP symptoms is limited.

引用

页码：636 / 646

页数：11

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