Multi-dimensional time-correlated single photon counting applied to diffuse optical tomography

We present a multi-dimensional TCSPC technique that combines multi-detector and multiplexing capability, and records fast and virtually unlimited sequences of time-of-flight distributions. The system consists of four fully parallel TCSPC channels. Each channel records simultaneously in up to eight detection channels. Up to four lasers and 32 source positions can be multiplexed. The total count rate is up to 4 x 10(7) photons per second. Time-of-flight sequences can be recorded with a resolution of 50 to 100 ms per curve. The system is operated within a single personal computer.