Should I stay or should I go: Wnt signals at the synapse

被引:9
|
作者
Davis, Elizabeth [1 ]
Ghosh, Anirvan [1 ]
机构
[1] Univ Calif San Diego, Div Biol, Neurobiol Sect, La Jolla, CA 92093 USA
关键词
D O I
10.1016/j.cell.2007.08.007
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Several extracellular factors, including Wnt proteins, have been reported to induce synapse formation. In this issue, Klassen and Shen ( 2007) report that Wnt proteins can also act as antisynaptogenic signals to prevent synapse formation in certain parts of the worm Caenorhabditis elegans. The differential response of axon populations to local Wnt proteins may contribute to the patterning of synaptic connections.
引用
收藏
页码:593 / 596
页数:4
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