The Joint Structural Biology Group beam lines at the ESRF: Modern macromolecular crystallography

被引：0
|
作者：
Mitchell, EP
机构：
[1] European Synchrotron Radiat Facil, F-38043 Grenoble, France
[2] European Mol Biol Lab, Grenoble Outstn, ILL, F-38042 Grenoble 9, France
来源：
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2001年 / 467卷
关键词：
macromolecular crystallography; protein; synchrotron beam line; MAD; automation; ESRF;
D O I：
10.1016/S0168-9002(01)00671-4
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
Macromolecular crystallography has evolved considerably over the last decade. Data sets in under an hour are now possible on high throughput beam lines leading to electron density and, possibly, initial models calculated on-site. There are five beam lines currently dedicated to macromolecular crystallography: the ID14 complex and BM-14 (soon to be superseded by ID-29). These lines handle over five hundred projects every six months and demand is increasing. Automated sample handling, alignment and data management protocols will be required to work efficiently with this demanding load. Projects developing these themes are underway within the JSBG. (C) 2001 Elsevier Science B.V. All rights reserved.
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页码：1372 / 1374
页数：3
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