Multiple sequence alignments as tools for protein structure and function prediction

被引：4

作者：

Valencia, A ^{[1
]}

机构：

[1] CSIC, CNB, Natl Biotechnol Ctr, Prot Design Grp, Madrid, Spain

来源：

COMPARATIVE AND FUNCTIONAL GENOMICS | 2003年 / 4卷 / 04期

关键词：

multiple sequence alignments; protein structure; prediction; protein interactions; correlated mutations; interaction networks;

D O I：

10.1002/cfg.313

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Multiple sequence alignments have much to offer to the understanding of protein structure, evolution and function. We are developing approaches to use this information in predicting protein-binding specificity, intra-protein and protein-protein interactions, and in reconstructing protein interaction networks. Copyright (C) 2003 John Wiley Sons, Ltd.

引用

页码：424 / 427

页数：4

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