Antispastic Management in Arterial Grafts in Coronary Artery Bypass Grafting Surgery

被引：25
|
作者：
He, Guo-Wei [1 ]
Taggart, David P.
机构：
[1] Hangzhou Normal Univ, Affiliated Hosp, Hangzhou, Zhejiang, Peoples R China
来源：
ANNALS OF THORACIC SURGERY | 2016年 / 102卷 / 02期
基金：
中国国家自然科学基金;
关键词：
INTERNAL MAMMARY ARTERY; HUMAN RADIAL ARTERY; HUMAN CONDUIT ARTERIES; THORACIC ARTERY; GASTROEPIPLOIC ARTERY; IN-VITRO; CLINICAL-IMPLICATIONS; SAPHENOUS-VEIN; NITROGLYCERIN SOLUTION; MEDIATED CONTRACTION;
D O I：
10.1016/j.athoracsur.2016.03.017
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Arterial grafts have long-term patency superior to vein grafts but have a tendency to develop spasm that can lead to potentially life-threatening complications. A perfect antispastic protocol should include advanced surgical technique and adequate pharmacologic methods. All pharmacologic vasodilator drugs relax the vessel through specific mechanisms, and therefore, there is no perfect, single best vasodilator to prevent or treat spasm of the arterial graft against all mechanisms of contraction. One of the choices is to use a combination of pharmacologic vasodilators targeting different mechanisms of spasm to obtain the reliable and best effect. (C) 2016 by The Society of Thoracic Surgeons
引用
收藏
页码：659 / 668
页数：10
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