Vitamin C Deficiency in Critically Ill Children: Prospective Observational Cohort Study

被引：7
|
作者：
Fathi, Alireza [1 ]
Downey, Corcoran [1 ]
Gohar, Aida Rabiee [2 ]
机构：
[1] Miller Childrens & Womens Hosp Long Beach, Pediat Crit Care Unit, 2801 Atlantic Ave, Long Beach, CA 90806 USA
[2] Univ West Virginia, Dept Pediat Crit Care, Morgantown, WV USA
来源：
PEDIATRIC CRITICAL CARE MEDICINE | 2022年 / 23卷 / 05期
关键词：
ascorbic acid; catabolic state; critically ill children; length of stay; vitamin C; vitamin C deficiency; ASCORBIC-ACID; SEPTIC SHOCK; PLASMA;
D O I：
10.1097/PCC.0000000000002914
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
OBJECTIVES: To evaluate the presence of vitamin C deficiency in critically ill children admitted to the PICU. DESIGN: Single-center prospective observational cohort study. SETTING: A 28-bed PICU and a pediatric outpatient sedation room of a tertiary-care teaching hospital. PATIENTS: Two pediatric patient groups 0-21 years old were studied: a PICU group and a group receiving deep sedation for elective outpatient procedures (noncritical care group). INTERVENTIONS: Vitamin C level was drawn for the PICU group within 24 hours of admission. Vitamin C level was drawn prior to start of deep sedation for the noncritical group. Measurement and Main Results: Vitamin C deficiency was present in 11/60 (18%) in the PICU group and 0/21 (0%) of the noncritical group (p < 0.05). CONCLUSIONS: Vitamin C deficiency was prevalent in our patients admitted to PICU.
引用
收藏
页码：395 / 398
页数：4
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