The use of lamotrigine in juvenile myoclonic epilepsy

被引：2
|
作者：
Buchanan, N [1 ]
机构：
[1] WESTMEAD HOSP,EPILEPSY UNIT,SYDNEY,NSW,AUSTRALIA
来源：
SEIZURE | 1996年 / 5卷 / 02期
关键词：
lamotrigine; juvenile myoclonic epilepsy; valproate side-effects; pregnancy; drug synergism;
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Lamotrigine (LTG) was used in 12 patients with juvenile myoclonic epilepsy (JME) who either had sodium valproate (VPA) side effects or did not wish to take VPA. Five patients are now fully controlled on LTG monotherapy. Side-effects were corrected by VPA withdrawal or reduction except for severe weight gain. In three patients it was not possible to withdraw VPA due to the re-emergence of myoclonus, suggesting LTG-VPA synergism. Two patients had successful pregnancies whilst taking LTG. Lamotrigine is a useful alternative in the management of JME.
引用
收藏
页码：149 / 151
页数：3
相关论文
共 50 条
  • [1] Exacerbation of juvenile myoclonic epilepsy with lamotrigine
    Biraben, A
    Allain, H
    Scarabin, JM
    Schück, S
    Edan, G
    [J]. NEUROLOGY, 2000, 55 (11) : 1758 - 1758
  • [2] Lamotrigine Monotherapy in Juvenile Myoclonic Epilepsy
    Kim, J.
    Choi, S-W.
    Sohn, M-J.
    [J]. EPILEPSIA, 2018, 59 : S276 - S276
  • [3] Outcome of lamotrigine treatment in juvenile myoclonic epilepsy
    Bodenstein-Sachar, H.
    Gandelman-Marton, R.
    Ben-Zeev, B.
    Chapman, J.
    Blatt, I.
    [J]. ACTA NEUROLOGICA SCANDINAVICA, 2011, 124 (01): : 22 - 27
  • [4] Lamotrigine for the treatment of juvenile myoclonic epilepsy.
    Sokic, DV
    Pavlovic, Z
    Jankovic, SM
    Levic, Z
    [J]. EPILEPSIA, 1999, 40 : 38 - 38
  • [5] Efficacy of lamotrigine in children with juvenile myoclonic epilepsy
    Mandelbaum, DE
    Venkatasubramanian, A
    Kugler, SL
    [J]. EPILEPSIA, 1999, 40 : 133 - 134
  • [6] FACTORS ASSOCIATED WITH THE OUTCOME OF LAMOTRIGINE TREATMENT IN JUVENILE MYOCLONIC EPILEPSY
    Bodenstein, H.
    Gandelman-Marton, R.
    Gidoni-Ben-Zeev, B.
    Blatt, I.
    [J]. EPILEPSIA, 2009, 50 : 191 - 191
  • [7] Exacerbation of juvenile myoclonic epilepsy with lamotrigine -: Reply from the authors
    Biraben, A
    Allain, H
    Scarabin, JM
    Schück, S
    Edan, G
    [J]. NEUROLOGY, 2001, 56 (10) : 1424 - 1425
  • [8] THE USE OF METHSUXIMIDE FOR JUVENILE MYOCLONIC EPILEPSY
    HURST, DL
    [J]. ANNALS OF NEUROLOGY, 1995, 38 (03) : 517 - 517
  • [9] Use of levetiracetam in juvenile myoclonic epilepsy
    Sharpe, DV
    Patel, A
    Fenichel, GM
    Abou-Khalil, B
    [J]. EPILEPSIA, 2005, 46 : 202 - 203
  • [10] Lamotrigine as first choice drug in juvenile myoclonic epilepsy treatment.
    Carignani, M
    [J]. EPILEPSIA, 1999, 40 : 283 - 283
12345