An anatomy ontology to represent biological knowledge in Dictyostelium discoideum

被引：32
|
作者：
Gaudet, Pascale [1 ]
Williams, Jeffery G. [2 ]
Fey, Petra [1 ]
Chisholm, Rex L. [1 ]
机构：
[1] Northwestern Univ, Ctr Genet Med, Chicago, IL 60611 USA
[2] Univ Dundee, Sch Life Sci, Dundee DD1 5EH, Scotland
来源：
BMC GENOMICS | 2008年 / 9卷 / 1期
基金：
英国惠康基金;
关键词：
D O I：
10.1186/1471-2164-9-130
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Background: Dictyostelium discoideum is a model system for studying many important physiological processes including chemotaxis, phagocytosis, and signal transduction. The recent sequencing of the genome has revealed the presence of over 12,500 protein-coding genes. The model organism database dictyBase hosts the genome sequence as well as a large amount of manually curated information. Results: We present here an anatomy ontology for Dictyostelium based upon the life cycle of the organism. Conclusion: Anatomy ontologies are necessary to annotate species-specific events such as phenotypes, and the Dictyostelium anatomy ontology provides an essential tool for curation of the Dictyostelium genome.
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页数：12
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