Vinyl radical cyclization onto imino group. Selective 6-endo cyclization onto aldimines leading to 3-methylenepiperidines

被引：32
|
作者：
Ryu, I [1 ]
Ogura, S [1 ]
Minakata, S [1 ]
Komatsu, M [1 ]
机构：
[1] Osaka Univ, Fac Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 08期
关键词：
D O I：
10.1016/S0040-4039(98)02666-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
When 5-exo/6-endo type of vinyl radical cyclization onto aldimine N=C bond was examined using tin hydride mediated radical reaction conditions, selective 6-endo cyclization took place to lead to 3-methylenepiperidines. On the other hand, vinyl radical cyclization onto ketimine N=C bond did not take place. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：1515 / 1518
页数：4
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