A new botulinum toxin type A free of complexing proteins for treatment of cervical dystonia

被引：206
|
作者：
Benecke, R
Jost, WH
Kanovsky, P
Ruzicka, E
Comes, G
Grafe, S
机构：
[1] Univ Rostock, Dept Neurol, D-18147 Rostock, Germany
[2] Deutsch Klin Diagnost, Dept Neurol, D-6200 Wiesbaden, Germany
[3] Masaryk Univ, Dept Neurol, Brno, Czech Republic
[4] Charles Univ, Dept Neurol, CR-11636 Prague, Czech Republic
[5] Merz Pharmaceut GmbH, Frankfurt, Germany
来源：
NEUROLOGY | 2005年 / 64卷 / 11期
关键词：
D O I：
10.1212/01.WNL.0000163767.99354.C3
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
A new botulinum toxin type A free of complexing proteins (NT 201) was compared with BOTOX in patients with cervical dystonia by means of a double-blind noninferiority trial. Four hundred sixty-three patients received IM injections of 70 to 300 U of NT 201 or BOTOX and were followed up over 16 weeks. The study clearly shows that NT 201 is at least as effective and safe as BOTOX.
引用
收藏
页码：1949 / 1951
页数：3
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