Inhibitory effects of 3-O-acyl-(+)-catechins on Epstein-Barr virus activation

被引：13

作者：

Uesato, S ^{[1
]}

Taniuchi, K

Kumagai, A

Nagaoka, Y

Seto, R

Hara, Y

Tokuda, H

Nishino, H

机构：

[1] Kansai Univ, Dept Biotechnol, Fac Engn, Suita, Osaka 5658680, Japan

[2] Kansai Univ, Org Res & Dev Innovat Sci & Technol, Suita, Osaka 5658680, Japan

[3] Tokyo Food Techno Co Ltd, Food Res Labs, Fujieda, Shizuoka 4260133, Japan

[4] Kyoto Prefectural Univ Med, Dept Biochem & Mol Biol, Kyoto 6020841, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2003年 / 51卷 / 12期

关键词：

(+)-catechin; 3-O-acyl-(+)-catechin; 3-O-acyl-(-)-epigallocatechin; Epstein-Barr virus early antigen (EBV-EA); activation; Uncaria gambir;

D O I：

10.1248/cpb.51.1448

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

In the course of an exploratory investigation of antitumor-promoting catechins, 3-O-acyl-(+)-catechins of varying carbon lengths from C-4 to C-18 were assessed for inhibitory effects on the activation of the Epstein-Barr virus early antigen. Like 3-O-acyl-(-)-epigallocatechins, the (+)-catechin derivatives showed promising effects with the C-3 acyl chain of C-8-C-11 carbon atoms.

引用

页码：1448 / 1450

页数：3

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