Hippocampal cytochrome oxidase activity of rats in easy and difficult visual discrimination learning

被引：8
|
作者：
Hu, D
Xu, XJ
Gonzalez-Lima, F
机构：
[1] MIT, McGovern Inst Brain Res, Cambridge, MA 02139 USA
[2] Grand Valley State Univ, Dept Psychol, Allendale, MI 49401 USA
[3] Univ Texas, Dept Psychol, Austin, TX 78712 USA
[4] Univ Texas, Inst Neurosci, Austin, TX 78712 USA
来源：
INTERNATIONAL JOURNAL OF NEUROSCIENCE | 2005年 / 115卷 / 05期
关键词：
CA1; CA2; cytochrome oxidase; dentate gyrus; discrimination learning; vicarious trial-and-error (VTE);
D O I：
10.1080/00207450590523440
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The present study investigated the functional involvement of the rat hippocampal formation in easy and difficult visual discrimination learning by measuring regional brain cytochrome oxidase (C.O.) activity, an index of neuronal metabolic activity. The results showed that learning was related to C.O. activity in the CA field and the dentate gyros of the hippocampal formation of rats in the difficult discrimination, whereas learning was related to C.O. activity only in the dentate gyrus of rats in the easy discrimination. The results suggest that difficult visual discrimination learning required greater involvement of the hippocampal formation than easy visual discrimination learning.
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页码：595 / 611
页数：17
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