ISSVA Classification of Vascular Anomalies and Molecular Biology

被引：110

作者：

Kunimoto, Kayo ^{[1
]}

Yamamoto, Yuki ^{[1
]}

Jinnin, Masatoshi ^{[1
]}

机构：

[1] Wakayama Med Univ, Dept Dermatol, Grad Sch Med, 811-1 Kimiidera, Wakayama 6410012, Japan

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2022年 / 23卷 / 04期

关键词：

venous malformation; lymphatic malformation; infantile hemangioma; RECEPTOR TYROSINE KINASE; INFANTILE HEMANGIOMA; SOMATIC MUTATION; MAP2K1; MUTATIONS; STEM-CELLS; EXPRESSION; VEGF;

D O I：

10.3390/ijms23042358

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Vascular anomalies include various diseases, which are classified into two types according to the International Society for the Study of Vascular Anomalies (ISSVA) classification: vascular tumors with proliferative changes of endothelial cells, and vascular malformations primarily consisting of structural vascular abnormalities. The most recent ISSVA classifications, published in 2018, detail the causative genes involved in many lesions. Here, we summarize the latest findings on genetic abnormalities, with the presentation of the molecular pathology of vascular anomalies.

引用

页数：13

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