Acute renal failure in a patient with mantle cell lymphoma

被引：7

作者：

Peddi, Sandeep ^{[1
]}

Ram, Rapur ^{[1
]}

Kataru, Sudheer Reddy ^{[2
]}

Chennu, Krishna Kishore ^{[1
]}

Nandyala, Rukumangadha ^{[3
]}

Kottu, Radhika ^{[3
]}

Kumar, V. Siva ^{[1
]}

机构：

[1] Sri Venkateswara Inst Med Sci, Dept Nephrol, Tirupati, Andhra Pradesh, India

[2] Sri Venkateswara Inst Med Sci, Dept Med Oncol, Tirupati, Andhra Pradesh, India

[3] Sri Venkateswara Inst Med Sci, Dept Pathol, Tirupati, Andhra Pradesh, India

来源：

HEMODIALYSIS INTERNATIONAL | 2015年 / 19卷 / 03期

关键词：

Acute renal failure; mantle cell lymphoma; crescentic glomerulonephritis; lymphomatous infiltration; renal biopsy; GLOMERULONEPHRITIS;

D O I：

10.1111/hdi.12229

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Mantle cell lymphoma is a rare form of B-cell lymphoma. We present a 54-year-old gentleman with mantle cell lymphoma. It was diagnosed based on the demonstration of B-cell antigens CD20 and CD5. It was further confirmed by demonstration of overexpression of cyclin D1 on these atypical lymphocytes in the immunohistochemical staining. He also had acute renal failure and proteinuria. Renal biopsy revealed crescents and lymphomatous infiltration of tubulointerstitium. The presence of infiltrating cells with similar markers in both the lymph node and the kidney confirmed the infiltration of kidney with lymphomatous cells. Our present patient, after a thorough literature search, is found to be the second one with a glomerular lesion and tubulointerstitial infiltration by malignant lymphoma cells.

引用

页码：E12 / E15

页数：4

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