Synthesis, crystal structure and absolute configuration of (+)-O-naphthyl cyclophosphorodiamidate

The title compound (+)-O-naphthyl cyclophosphorodiamidate (C32H35N2O2P, M-r=510. 59) has been synthesized and characterized by P-31 NMR, H-1 NMR and elemental analysis. X-ray diffraction analysis at 273(2) K indicates that the compound belongs to orthorhombic system, space group P2(1)2(1)2(1) with cell parameters: a=1. 002 8(4) nm, b=1. 140 6(4) nm, c=2. 445 5(8) nm, V=2.797 108) nm(3), Z=4, D-C = 1. 212 g/cm(3), F (000) = 1 088, mu= 0. 129 mm(-1). The structure parameters were refined by full-matrix least-squares on F-2 to R=0. 058 5 and WR=0. 082 7. The flack x pamameter was 0. 03(12). The absolute configuration of the phosphorus in the title compound is S.