Characterization of Bacillus subtilis clones surviving overproduction of Zeta, a pSM19035 plasmid-encoded toxin

被引：0

作者：

Nowakowska, B ^{[1
]}

Kern-Zdanowicz, I ^{[1
]}

Zielenkiewicz, U ^{[1
]}

Ceglowski, P ^{[1
]}

机构：

[1] Polish Acad Sci, Inst Biochem & Biophys, PL-02106 Warsaw, Poland

来源：

ACTA BIOCHIMICA POLONICA | 2005年 / 52卷 / 01期

关键词：

plasmid stable maintenance; postsegregational killing; toxin; Gram positive bacteria;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The postsegregational killing system of pSM19035 plasmid consists of the proteins Zeta and Epsilon, a toxin and an antidote, respectively. Zeta mutants were isolated with the use of Bacillus subtilis strain with the xi gene under control of an inducible promoter integrated into the chromosome. Results of mutant analysis point to the amino terminal part of the Zeta protein as being responsible for the toxicity.

引用

页码：99 / 107

页数：9

共 23 条

[1] The ClpXP Protease Is Responsible for the Degradation of the Epsilon Antidote to the Zeta Toxin of the Streptococcal pSM19035 Plasmid
Brzozowska, Iwona
Zielenkiewicz, Urszula
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (11) : 7514 - 7523
[2] The toxin-antitoxin system of the streptococcal plasmid pSM19035
Zielenkiewicz, U
Ceglowski, P
[J]. JOURNAL OF BACTERIOLOGY, 2005, 187 (17) : 6094 - 6105
[3] Characterization of a novel partition system encoded by the δ and ω genes from the streptococcal plasmid pSM19035
Dmowski, M
Sitkiewicz, I
Ceglowski, P
[J]. JOURNAL OF BACTERIOLOGY, 2006, 188 (12) : 4362 - 4372
[4] In Vivo Interactions between Toxin-Antitoxin Proteins Epsilon and Zeta of Streptococcal Plasmid pSM19035 in Saccharomyces cerevisiae
Zielenkiewicz, Urszula
Kowalewska, Magdalena
Kaczor, Celina
Ceglowski, Piotr
[J]. JOURNAL OF BACTERIOLOGY, 2009, 191 (11) : 3677 - 3684
[5] A NOVEL SITE-SPECIFIC RECOMBINASE ENCODED BY THE STREPTOCOCCUS-PYOGENES PLASMID PSM19035
ROJO, F
ALONSO, JC
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1994, 238 (02) : 159 - 172
[6] Crystal structure of ω transcriptional repressor encoded by Streptococcus pyogenes plasmid pSM19035 at 1.5 A resolution
Murayama, K
Orth, P
de la Hoz, AB
Alonso, JC
Saenger, W
[J]. JOURNAL OF MOLECULAR BIOLOGY, 2001, 314 (04) : 789 - 796
[7] STABILIZATION OF A PLASMID-ENCODED LACZ PHENOTYPE IN BACILLUS-SUBTILIS
SHOHAM, Y
DEMAIN, AL
[J]. CURRENT MICROBIOLOGY, 1990, 20 (06) : 373 - 379
[8] Crystallization and preliminary X-ray diffraction studies of the εζ addiction system encoded by Streptococcus pyogenes plasmid pSM19035
Meinhart, A
Alings, C
Sträter, N
Camacho, AG
Alonso, JC
Saenger, W
[J]. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 2001, 57 : 745 - 747
[9] THE BACILLUS-SUBTILIS HISTONE-LIKE PROTEIN HBSU IS REQUIRED FOR DNA RESOLUTION AND DNA INVERSION MEDIATED BY THE BETA-RECOMBINASE OF PLASMID PSM19035
ALONSO, JC
WEISE, F
ROJO, F
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (07) : 2938 - 2945
[10] PURIFICATION OF THE BETA-PRODUCT ENCODED BY THE STREPTOCOCCUS-PYOGENES PLASMID PSM19035 - A PUTATIVE DNA RECOMBINASE REQUIRED TO RESOLVE PLASMID OLIGOMERS
ROJO, F
WEISE, F
ALONSO, JC
[J]. FEBS LETTERS, 1993, 328 (1-2) : 169 - 173

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