Total agenesis of the corpus callosum in a patient with childhood-onset schizophrenia

被引：13

作者：

Cecilio Hallak, Jaime Eduardo ^{[1
]}

de Sousa Crippa, Jose Alexandre ^{[1
]}

Pinto, Joe Porfirio ^{[1
]}

Machado de Sousa, Joao Paulo ^{[1
]}

Trzesniak, Clarissa ^{[1
]}

Dursun, Serdar Murat ^{[2
]}

McGuire, Phillip ^{[3
]}

William Deakin, John Francis ^{[2
]}

Zuardi, Antonio Waldo ^{[1
]}

机构：

[1] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Neurol Psychiat & Psychol Med, BR-14049 Ribeirao Preto, SP, Brazil

[2] Univ Manchester, Neurosci & Psychiat Unit, Manchester, Lancs, England

[3] Inst Psychiat, Dept Psychol Med, London SE5 8AF, England

来源：

ARQUIVOS DE NEURO-PSIQUIATRIA | 2007年 / 65卷 / 4B期

关键词：

schizophrenia; corpus callosum; agenesis;

D O I：

10.1590/S0004-282X2007000700024

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The hypothesis that schizophrenia involves aberrant inter-hemispheric communication has a long pedigree, however its precise role remains unclear. We therefore report the case of a total agenesis of the corpus callosum in a 21-year-old man with childhood-onset schizophrenia. The presence of schizophrenia with very early onset on absence of corpus callosum offers an opportunity to examine neurodevelopmental model and theories regarding to interhemispheric communication in the pathogenesis of psychosis.

引用

页码：1216 / 1219

页数：4

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