Comprehensive proteomic profiling of serum extracellular vesicles in patients with colorectal liver metastases identifies a signature for non-invasive risk stratification and early-response evaluation

被引：14

作者：

Lin, Kuailu ^{[1
,2
]}

Baenke, Franziska ^{[1
,3
]}

Lai, Xixi ^{[1
,4
]}

Schneider, Martin ^{[5
,8
]}

Helm, Dominic ^{[5
]}

Polster, Heike ^{[1
]}

Rao, Venkatesh S. ^{[1
]}

Ganig, Nicole ^{[1
,3
]}

Wong, Fang Cheng ^{[1
]}

Seifert, Lena ^{[1
,3
,6
]}

Seifert, Adrian M. ^{[1
,3
,6
]}

Jahnke, Beatrix ^{[1
]}

Kretschmann, Nicole ^{[7
]}

Ziemssen, Tjalf ^{[7
]}

Klupp, Fee ^{[8
]}

Schmidt, Thomas ^{[8
,9
]}

Schneider, Martin ^{[5
,8
]}

Han, Yi ^{[1
]}

Weber, Tim F. ^{[10
]}

Plodeck, Verena ^{[11
]}

Nebelung, Heiner ^{[11
]}

Schmitt, Nathalie ^{[12
]}

Korell, Felix ^{[12
,13
]}

Koehler, Bruno C. ^{[12
,14
]}

Riediger, Carina ^{[1
]}

Weitz, Juergen ^{[1
,3
,6
]}

Rahbari, Nuh N. ^{[15
]}

Kahlert, Christoph ^{[1
,3
,6
]}

机构：

[1] Tech Univ Dresden, Carl Gustav Carus Univ Hosp Dresden, Dept Visceral Thorac & Vasc Surg, Fetscherstr 74, D-01307 Dresden, Germany

[2] Zhejiang Univ, Affiliated Hosp 1, Dept Breast Surg, Coll Med, Hangzhou, Peoples R China

[3] German Canc Res Ctr, German Canc Consortium DKTK, Partner Site Dresden, Heidelberg, Germany

[4] Zhejiang Univ, Sir Run Run Shaw Hosp, Dept Resp & Crit Care Med, Coll Med, Hangzhou, Peoples R China

[5] German Canc Res Ctr, MS Based Prot Anal Unit, Heidelberg, Germany

[6] Natl Ctr Tumor Dis NCT UCC, Partner Site Dresden, Heidelberg, Germany

[7] Carl Gustav Carus Univ Hosp Dresden, Dept Neurol, Ctr Clin Neurosci, MS Ctr, Dresden, Germany

[8] Univ Hosp Heidelberg, Dept Gen Visceral & Transplantat Surg, Heidelberg, Germany

[9] Univ Klinikum Koln, Klin Allgemein Viszeral Tumor & Transplantationsc, Kerpener Str 62, D-50937 Cologne, Germany

[10] Heidelberg Univ Hosp, Diagnost & Intervent Radiol DiR, Neuenheimer Feld 420, D-69120 Heidelberg, Germany

[11] Carl Gustav Carus Univ Hosp Dresden, Dept Diagnost & Intervent Radiol, Dresden, Germany

[12] Univ Hosp Heidelberg, Liver Canc Ctr Heidelberg, Natl Ctr Tumour Dis, Dept Med Oncol, Heidelberg, Germany

[13] Heidelberg Univ, Dept Med 5, Heidelberg, Germany

[14] German Canc Consortium DKTK, D-69120 Heidelberg, Germany

[15] Heidelberg Univ, Univ Med Mannheim, Med Fac Mannheim, Dept Surg, D-68167 Mannheim, Germany

来源：

MOLECULAR CANCER | 2022年 / 21卷 / 01期

关键词：

Extracellular vesicles; Protein signature; Molecular risk stratification; Early response prediction; Colorectal liver metastases; BIOMARKERS; EXOSOMES; CANCER;

D O I：

10.1186/s12943-022-01562-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页数：7

共 6 条

[1] Comprehensive proteomic profiling of serum extracellular vesicles in patients with colorectal liver metastases identifies a signature for non-invasive risk stratification and early-response evaluation
Kuailu Lin
Franziska Baenke
Xixi Lai
Martin Schneider
Dominic Helm
Heike Polster
Venkatesh S. Rao
Nicole Ganig
Fang Cheng Wong
Lena Seifert
Adrian M. Seifert
Beatrix Jahnke
Nicole Kretschmann
Tjalf Ziemssen
Fee Klupp
Thomas Schmidt
Martin Schneider
Yi Han
Tim F. Weber
Verena Plodeck
Heiner Nebelung
Nathalie Schmitt
Felix Korell
Bruno C. Köhler
Carina Riediger
Jürgen Weitz
Nuh N. Rahbari
Christoph Kahlert
Molecular Cancer, 21
[2] Plasma extracellular vesicle messenger RNA profiling identifies prognostic EV signature for non-invasive risk stratification for survival prediction of patients with pancreatic ductal adenocarcinoma
Yi Han
Pascal Drobisch
Alexander Krüger
Doreen William
Konrad Grützmann
Lukas Böthig
Heike Polster
Lena Seifert
Adrian M. Seifert
Marius Distler
Mathieu Pecqueux
Carina Riediger
Verena Plodeck
Heiner Nebelung
Georg F. Weber
Christian Pilarsky
Ulf Kahlert
Ulf Hinz
Susanne Roth
Thilo Hackert
Jürgen Weitz
Fang Cheng Wong
Christoph Kahlert
Journal of Hematology & Oncology, 16
[3] Plasma extracellular vesicle messenger RNA profiling identifies prognostic EV signature for non-invasive risk stratification for survival prediction of patients with pancreatic ductal adenocarcinoma
Han, Yi
Drobisch, Pascal
Krueger, Alexander
William, Doreen
Gruetzmann, Konrad
Boethig, Lukas
Polster, Heike
Seifert, Lena
Seifert, Adrian M.
Distler, Marius
Pecqueux, Mathieu
Riediger, Carina
Plodeck, Verena
Nebelung, Heiner
Weber, Georg F.
Pilarsky, Christian
Kahlert, Ulf
Hinz, Ulf
Roth, Susanne
Hackert, Thilo
Weitz, Juergen
Wong, Fang Cheng
Kahlert, Christoph
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2023, 16 (01)
[4] TRANSCRIPTOMIC PROFILING IDENTIFIES A NOVEL, NON-INVASIVE, MICRORNA SIGNATURE FOR THE DIAGNOSIS OF PATIENTS WITH EARLY-ONSET COLORECTAL CANCER (EOCRC)
Hernandez, Goretti
Banwait, Jasjit K.
Kandimalla, Raju
Gonzalez-Lopez, Natalia
Perea, Jose
Bujanda, Luis
Balaguer, Francesc
Quintero, Enrique
Goel, Ajay
GASTROENTEROLOGY, 2019, 156 (06) : S945 - S945
[5] PROTEIN SURFACE SIGNATURE ON SERUM EXTRACELLULAR VESICLES FOR NON-INVASIVE DETECTION OF TUMOR PROGRESSION IN GLIOBLASTOMA PATIENTS
Tzaridis, Theophilos
Weller, Johannes
Bachurski, Daniel
Shakheri, Farhad
Schaub, Christina
Hau, Peter
Buness, Andreas
Schlegel, Uwe
Steinbach, Joachim
Seidel, Clemens
Goldbrunner, Roland
Schaefer, Niklas
Wechsler-Reya, Robert
Scheffler, Bjoern
Glas, Martin
Haeberle, Lothar
Herrlinger, Ulrich
Coch, Christoph
Reiners, Katrin
Hartmann, Gunther
NEURO-ONCOLOGY, 2021, 23 : 15 - 16
[6] A comprehensive proteomic profiling of urinary exosomes and the identification of early non-invasive biomarker in patients with coronary artery disease
Sharma, Pratibha
Roy, Ambuj
Dhamija, Rajinder K.
Bhushan, Sudha
Baswal, Kamal
Kulandaisamy, Rajkumar
Yadav, Satyavir
Kumar, Saroj
Inampudi, Krishna Kishore
JOURNAL OF PROTEOMICS, 2024, 293

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