Checkpoint Inhibitors Augment CD19-Directed Chimeric Antigen Receptor (CAR) T Cell Therapy in Relapsed B-Cell Acute Lymphoblastic Leukemia

被引：105
|
作者：
Li, Amanda M. [1 ]
Hucks, George E. [2 ]
Dinofia, Amanda M. [3 ]
Seif, Alix E. [4 ]
Teachey, David T. [4 ,5 ]
Baniewicz, Diane [3 ]
Callahan, Colleen [3 ]
Fasano, Christina [3 ]
McBride, Beth [3 ]
Gonzalez, Vanessa [6 ]
Nazimuddin, Farzana [7 ]
Porter, David L. [8 ]
Lacey, Simon F. [9 ]
June, Carl H. [9 ]
Grupp, Stephan A. [10 ,11 ]
Maude, Shannon L. [4 ,5 ,10 ,11 ]
机构：
[1] British Columbia Childrens Hosp, Div Oncol, Vancouver, BC, Canada
[2] Univ N Carolina, Div Pediat Hematol Oncol & Bone Marrow Transplant, Chapel Hill, NC 27515 USA
[3] Childrens Hosp Philadelphia, Div Oncol, Canc Immunotherapy Program, Philadelphia, PA 19104 USA
[4] Childrens Hosp Philadelphia, Div Oncol, Philadelphia, PA 19104 USA
[5] Childrens Hosp Philadelphia, Ctr Childhood Canc Res, Philadelphia, PA 19104 USA
[6] Univ Penn, Sch Med, Ctr Cellular Immunotherapies, Philadelphia, PA 19104 USA
[7] Univ Penn, Philadelphia, PA 19104 USA
[8] Univ Penn, Abramson Canc Ctr, Div Hematol & Oncol, Philadelphia, PA 19104 USA
[9] Univ Penn, Ctr Cellular Immunotherapies, Philadelphia, PA 19104 USA
[10] Childrens Hosp Philadelphia, Ctr Childhood Canc Res, Div Oncol, Philadelphia, PA 19104 USA
[11] Childrens Hosp Philadelphia, Canc Immunotherapy Program, Philadelphia, PA 19104 USA
来源：
BLOOD | 2018年 / 132卷
关键词：
D O I：
10.1182/blood-2018-99-112572
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
556
引用
收藏
页数：3
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