A new picrotoxane sesquiterpene from the berries of Baccaurea ramiflora with antifungal activity against Colletotrichum gloeosporioides

被引：14
|
作者：
Pan, Zheng-Hong [1 ]
Ning, De-Sheng [1 ]
Huang, Si-Si [1 ]
Wu, Yun-Fei [2 ]
Ding, Tao [1 ]
Luo, Lei [2 ]
机构：
[1] Guangxi Zhuang Autonomous Reg & Chinese Acad Sci, Guangxi Inst Bot, Guangxi Key Lab Funct Phytochem Res & Utilizat, Guilin 541006, Peoples R China
[2] Yunnan Normal Univ, Fac Chem & Chem Engn, Kunming 650500, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2015年 / 29卷 / 14期
基金：
中国国家自然科学基金;
关键词：
ramifloside; sesquiterpene glycoside; Baccaurea ramiflora; picrotoxane; antifungal activity;
D O I：
10.1080/14786419.2014.999335
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Three picrotoxane sesquiterpenes including one new glycoside and two known constituents, sapidolide A (2) and picrotoximaesin (3), were isolated from the berries of Baccaurea ramiflora. The structure of the new sesquiterpene glycoside, ramifloside (1), was elucidated as 2-one-6 alpha-hydroxy-13-nor-11-picrotoxen-3(15 beta)-olide 10-O-beta-d-glucopyranoside on the basis of extensive spectroscopic analysis. Compounds 1-3 exhibited antifungal activity against Colletotrichum gloeosporioides with MICs of 12.5, 12.5 and 50 mu g/mL.
引用
收藏
页码：1323 / 1327
页数：5
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