Biotransformation of squamulosone by Curvularia lunata ATCC 12017

被引:22
|
作者
Collins, DO
Buchanan, GO
Reynolds, WF
Reese, PB [1 ]
机构
[1] Univ W Indies, Dept Chem, Kingston 7, Jamaica
[2] Univ Toronto, Dept Chem, Toronto, ON M5S 3H6, Canada
关键词
Curvularia lunata ATCC 12017; squamulosone; biotransformation; hydroxylation; Hyptis verticillata; aromadendrane; cadinane; sesquiterpene;
D O I
10.1016/S0031-9422(01)00060-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Squamulosone (aromadendr-1(10)-en-9-one). isolated in large quantity from the plant Hyptis verticillata Jacq. (Labiatae), was incubated with the fungus Curvularia lunata ATCC 12017 in two different growth media. Six metabolites were isolated from each medium, with five of the products being common to both fermentations. All seven metabolites are novel. The insecticidal activity of these aromadendranes was evaluated against the sweet potato weevil Cylas formicarius elegantulus. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:377 / 383
页数:7
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