Hierarchical reinforcement learning for automatic disease diagnosis

被引:11
|
作者
Zhong, Cheng [1 ]
Liao, Kangenbei [1 ]
Chen, Wei [1 ]
Liu, Qianlong [2 ]
Peng, Baolin [3 ]
Huang, Xuanjing [4 ]
Peng, Jiajie [5 ]
Wei, Zhongyu [1 ,5 ]
机构
[1] Fudan Univ, Sch Data Sci, Shanghai 200433, Peoples R China
[2] Alibaba Grp, Hangzhou 310052, Peoples R China
[3] Microsoft Res, Redmond, WA 98052 USA
[4] Fudan Univ, Sch Comp Sci, Shanghai 200433, Peoples R China
[5] Fudan Univ, Res Inst Intelligent Complex Symtems, Shanghai 200433, Peoples R China
关键词
D O I
10.1093/bioinformatics/btac408
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Motivation: Disease diagnosis-oriented dialog system models the interactive consultation procedure as the Markov decision process, and reinforcement learning algorithms are used to solve the problem. Existing approaches usually employ a flat policy structure that treat all symptoms and diseases equally for action making. This strategy works well in a simple scenario when the action space is small; however, its efficiency will be challenged in the real environment. Inspired by the offline consultation process, we propose to integrate a hierarchical policy structure of two levels into the dialog system for policy learning. The high-level policy consists of a master model that is responsible for triggering a low-level model, the low-level policy consists of several symptom checkers and a disease classifier. The proposed policy structure is capable to deal with diagnosis problem including large number of diseases and symptoms. Results: Experimental results on three real-world datasets and a synthetic dataset demonstrate that our hierarchical framework achieves higher accuracy and symptom recall in disease diagnosis compared with existing systems. We construct a benchmark including datasets and implementation of existing algorithms to encourage follow-up researches.
引用
收藏
页码:3995 / 4001
页数:7
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