Prevalence and associated factors for delirium in critically ill patients at a Japanese intensive care unit

被引:48
|
作者
Tsuruta, Ryosuke [1 ]
Nakahara, Takashi [1 ]
Miyauchi, Takashi [1 ]
Kutsuna, Satoshi [1 ]
Ogino, Yasuaki [1 ]
Yamamoto, Takahiro [1 ]
Kaneko, Tadashi [1 ]
Kawamura, Yoshikatsu [1 ]
Kasaoka, Shunji [2 ]
Maekawa, Tsuyoshi [1 ,2 ]
机构
[1] Yamaguchi Univ, Adv Med Emergency & Crit Care Ctr, Yamaguchi 7558505, Japan
[2] Yamaguchi Univ, Grad Sch Med, Dept Crit Care & Emergency Med & Stress & Bioresp, Yamaguchi, Japan
关键词
Delirium; Inflammation; C-Reactive protein (CRP); Confusion Assessment Method for the Intensive Care Unit (CAM-ICU); Ventilator; MECHANICALLY VENTILATED PATIENTS; CONFUSION ASSESSMENT METHOD; AGITATION-SEDATION SCALE; INDEPENDENT RISK-FACTOR; C-REACTIVE PROTEIN; MOTORIC SUBTYPES; ICU PATIENTS; RELIABILITY; MECHANISMS; VALIDITY;
D O I
10.1016/j.genhosppsych.2010.09.001
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: To investigate the prevalence and associated factors of delirium in critically ill patients during an intensive care unit (ICU) stay. Methods: We investigated 103 of 172 patients admitted consecutively to a university-based 20-bed ICU in a 3-month period. Six ICU physicians, who were familiar with the Confusion Assessment Method for the ICU (CAM-ICU), assessed patient delirium daily. Patient demographics, diagnosis, Acute Physiology and Chronic Health Evaluation (APACHE) II score, mechanical ventilation and maximum serum C-reactive protein (max-CRP) level during the ICU stay (max-CRP) were compared between patients who developed delirium and those who did not. Results: Twenty-one (20%) of 103 patients and 13(76%) of 17 mechanically ventilated patients developed delirium. APACHE II scores and max-CRP were significantly higher in patients who experienced delirium than in those who did not (P <.001). Use of a mechanical ventilator (P=.002), max-CRP (P=.032) and length of ICU stay (P=.043) were identified as independent associations for delirium development. Conclusions: The prevalence of delirium was 20% in ICU patients and 80% in ventilated patients in a Japanese ICU. (c) 2010 Elsevier Inc. All rights reserved.
引用
收藏
页码:607 / 611
页数:5
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