Primus inter pares (First among equals)

被引：0
|
作者：
Keck, JL [1 ]
Berger, JM [1 ]
机构：
[1] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
来源：
NATURE STRUCTURAL BIOLOGY | 2001年 / 8卷 / 01期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Priming of DNA replication in eukaryotes is carried out by a heterotetrameric complex known as pol alpha -primase. The structure of the Pyrococcus furiosus RNA polymerase subunit of this complex shows that priming is carried out by unrelated proteins in archaea/eukarya and eubacteria, provides insights into the mechanism of action of a novel RNA polymerase, and raises new questions regarding the ancestry of priming and replication in the three domains of life.
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页码：2 / 4
页数：3
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