Heterotopic Ossification After Spinal Cord Injury: Current Clinical Approaches

被引：4
|
作者：
Zakel, Juliet C. [1 ,2 ]
Harrington, Amanda L. [1 ,2 ]
机构：
[1] Univ Pittsburgh, UPMC Rehabil Inst, UPMC Mercy, PM&R Off,Med Ctr, 1400 Locust St Bldg D,Suite G103, Pittsburgh, PA 15219 USA
[2] Univ Pittsburgh, Dept Phys Med & Rehabil, Sch Med, Kaufmann Med Bldg,Suite 910,3471 Fifth Ave, Pittsburgh, PA 15213 USA
来源：
CURRENT PHYSICAL MEDICINE AND REHABILITATION REPORTS | 2020年 / 8卷 / 03期
关键词：
Heterotopic ossification; Spinal cord injury; TOTAL HIP-ARTHROPLASTY; TRAUMATIC BRAIN; EARLY-DIAGNOSIS; ALKALINE-PHOSPHATASE; PROSTAGLANDIN E-2; BONE-FORMATION; RISK-FACTORS; CLASSIFICATION; PREVENTION; RESECTION;
D O I：
10.1007/s40141-020-00271-7
中图分类号：
R49 [康复医学];
学科分类号：
100215 ;
摘要：
Purpose of ReviewHeterotopic ossification (HO) is a frequent complication after spinal cord injury (SCI). This review article critically analyzes the scientific literature of HO after SCI and offers expert opinion on how past research translates to clinical practice.Recent FindingsTriple-phase bone scintigraphy has been the gold standard for diagnosing HO; however, recent research suggests diagnostic ultrasound may be more convenient, cost-effective, and safe. Currently, routine pharmaceutical prophylaxis for HO after SCI is not recommended. Range of motion exercises are advised to prevent and treat HO. Etidronate was approved for HO treatment, but it is no longer available in the USA. Evidence to support the use of alternate bisphosphonates is lacking. Surgical resection is reserved for select cases where the primary goal is improving function.SummaryHO is a common complication after SCI, and continued research is needed to improve diagnosis, prevention, and treatment.
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页码：172 / 178
页数：7
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