Creatinine imprinted poly(hydroxyethyl methacrylate) based cryogel cartridges

被引：5
|
作者：
Topcu, Aykut Arif [1 ,2 ]
Bereli, Nilay [2 ]
Albayrak, Irfan [1 ]
Denizli, Adil [2 ]
机构：
[1] Krkkale Univ, Dept Biol, Krkkale, Turkey
[2] Hacettepe Univ, Dept Chem, Ankara, Turkey
来源：
JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY | 2017年 / 54卷 / 08期
关键词：
Creatinine; creatinine adsorption; cryogel; molecular imprinting; MODIFIED PRECIPITATION POLYMERIZATION; SUPERMACROPOROUS CRYOGELS; RECOGNITION; MATRIX; POLYMERS; AFFINITY; RECEPTOR; BINDING; CHROMATOGRAPHY; PURIFICATION;
D O I：
10.1080/10601325.2017.1320756
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Creatinine imprinted cryogel (MIP) cartridge was prepared with functional monomer N-methacryloyl-(L)-histidinemethylester (MAH) under frozen conditions. Creatinine adsorption studies and selectivity of MIP cryogel were evaluated in aqueous solution and artificial urine sample. Maximum adsorbed amount of creatinine was calculated as 6.83mg/g polymer for MIP cryogel. Langmuir and Freundlich adsorption isotherm models were used to investigate the adsorption behaviour of creatinine. In the artificial urine sample; recovery amounts of creatinine were found 34.7-46.2%. Creatinine imprinted cryogel (MIP) cartridge recognized creatinine, 4.58 and 4.37times greater competitive molecules. MIP cryogel catridge was repeatedly used many times for adsorption desorption cycles.
引用
收藏
页码：495 / 501
页数：7
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