Current status of gene therapy in melanoma treatment

被引：4

作者：

Wang, Yonglu ^{[1
,2
]}

You, Wei ^{[1
]}

Li, Xueming ^{[3
,4
]}

机构：

[1] Nanjing Tech Univ, Coll Pharm, Nanjing, Peoples R China

[2] Univ Saskatchewan, Coll Pharm & Nutr, Saskatoon, SK, Canada

[3] Nanjing Bestform Pharmaceut Technol Co Ltd, Nanjing, Peoples R China

[4] Nanjing Tech Univ, Postgrad Dept, Nanjing, Peoples R China

来源：

BIOCELL | 2020年 / 44卷 / 02期

关键词：

Gene therapy; Melanoma; Viral delivery system; Nanoparticles; TUMOR-SUPPRESSOR; GM-CSF; CANCER; ONCOGENES; INFLAMMATION; DELIVERY; PEPTIDE;

D O I：

10.32604/biocell.2020.09023

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Melanoma is the deadliest type of skin cancer and which has a high ability of metastasis. Surgery is an effective method to treat I or II stage melanoma patients. However, there are few treatment options for metastatic melanoma. Gene therapy is one of the attractive options and is considered as the future direction for treating melanoma. This review mainly discusses the properties and challenges of the various gene therapies in melanoma, especially the delivery systems and gene targeting.

引用

页码：167 / 174

页数：8

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