Detection and sequence analysis of hepatitis B virus integration in peripheral blood mononuclear cells

被引：37
|
作者：
Laskus, T
Radkowski, M
Wang, LF
Nowicki, M
Rakela, J
机构：
[1] Univ Pittsburgh, Med Ctr, Div Gastroenterol & Hepatol, Pittsburgh, PA 15213 USA
[2] Inst Infect Dis, Warsaw, Poland
[3] Univ So Calif, Maternal Child Virol Res Lab, Los Angeles, CA 90033 USA
来源：
JOURNAL OF VIROLOGY | 1999年 / 73卷 / 02期
关键词：
D O I：
10.1128/JVI.73.2.1235-1238.1999
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A PCR-based technique was used to detect hepatitis B virus (HBV) integration in peripheral blood mononuclear cells from patients with chronic hepatitis B. Integrated HBV DNA sequences, with virus-cell junctions located in the cohesive region between direct repeat 1 (DR1) and DR2, were found in 2 of 10 studied patients.
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页码：1235 / 1238
页数：4
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