Role of non-catalytic p101 subunit in regulation of phosphoinositide 3-kinase γ enzymatic activities

被引:0
|
作者
Shymanets, A. [1 ]
Ahmadian, M. R. [1 ]
Nuernberg, B. [1 ]
机构
[1] Univ Dusseldorf, Univ Hosp & Clin, Inst Biochem & Mol Biol 2, Dusseldorf, Germany
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
86
引用
收藏
页码:25 / 25
页数:1
相关论文
共 50 条
  • [1] The role of non-catalytic p101 and p87 subunits in regulating phosphoinositide 3-kinase γ by Gβγ and H-Ras
    Shymanets, A.
    Ahmadian, M. R.
    Krause, E.
    Wetzker, R.
    Harteneck, C.
    Nuernberg, B.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2012, 385 : 88 - 89
  • [2] Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase γ
    Voigt, P
    Brock, C
    Nürnberg, B
    Schaefer, M
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (06) : 5121 - 5127
  • [3] Defining functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase γ
    Voigt, P
    Nürnberg, B
    Schultz, G
    Schaefer, M
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2004, 369 : R46 - R46
  • [4] Roles of Gβγ in membrane recruitment and activation of p110γ/p101 phosphoinositide 3-kinase γ
    Brock, C
    Schaefer, M
    Reusch, HP
    Czupalla, C
    Michalke, M
    Spicher, K
    Schultz, G
    Nürnberg, B
    JOURNAL OF CELL BIOLOGY, 2003, 160 (01): : 89 - 99
  • [5] The catalytic subunit of phosphoinositide 3-kinase: Requirements for oncogenicity
    Aoki, M
    Schetter, C
    Himly, M
    Batista, O
    Chang, HW
    Vogt, PK
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (09) : 6267 - 6275
  • [6] Gβγ recruits heterodimeric phosphatidylinositide 3-kinase γ to the cell membrane through interaction with its non-catalytic p101-subunit
    Brock, C
    Schaefer, M
    Czupalla, C
    Reusch, HP
    Schulz, A
    Nürnberg, B
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2002, 365 : R46 - R46
  • [7] Characterizing the interactions between the two subunits of the p101/p110γ phosphoinositide 3-kinase and their role in the activation of this enzyme by Gβγ subunits
    Krugmann, S
    Hawkins, PT
    Pryer, N
    Braselmann, S
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (24) : 17152 - 17158
  • [8] The phosphoinositide-3-kinase p101 subunit facilitates membrane translocation of PI3K allowing direct interaction of Gβγ with the catalytic p110γ subunit
    Leopoldt, D
    Maier, U
    Exner, T
    Nürnberg, B
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1998, 358 (01) : R657 - R657
  • [9] Roles of non-catalytic subunits in Gβγ-induced activation of class I phosphoinositide 3-kinase isoforms β and γ
    Maier, U
    Babich, A
    Nürnberg, B
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (41) : 29311 - 29317
  • [10] A biochemical mechanism for the oncogenic potential of the p110β catalytic subunit of phosphoinositide 3-kinase
    Dbouk, Hashem A.
    Pang, Huan
    Fiser, Andras
    Backer, Jonathan M.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (46) : 19897 - 19902