High resolution read-out circuit for DNA label-free detection system

被引：0

作者：

De Venuto, Daniela ^{[1
]}

Ricco, Bruno ^{[2
]}

机构：

[1] DEE Politecn Bari, Bari, Italy

[2] Univ Bologna, DEIS, Bologna, Italy

来源：

ISQED 2008: PROCEEDINGS OF THE NINTH INTERNATIONAL SYMPOSIUM ON QUALITY ELECTRONIC DESIGN | 2008年

关键词：

DNA biosensor read-out; charge sensitive front-end; differential read-out system;

D O I：

10.1109/ISQED.2008.153

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

This paper presents novel read-out electronic systems for a fast DNA label-less detection. The capacitive shift due to the hybridization effect is monitored by means of a charge sensitive amplifier and a differential stage. The systems provide an AID conversion and an evaluation of the capacitive shift amount with a resolution of 11 bit. The read-out solutions demonstrate the ability to identify a 0.01% variation on the capacitive value of the sensor. The investigated techniques are suitable for monolithic systems or for a micro-fabricated array of sensors.

引用

页码：708 / +

页数：2

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