Non-Classical Structures Among Current Platinum Complexes with Potential as Antitumor Drugs

被引：15
|
作者：
Quiroga, Adoracion G. [1 ]
机构：
[1] Univ Autonoma Madrid, Dept Quim Inorgan, E-28049 Madrid, Spain
来源：
CURRENT TOPICS IN MEDICINAL CHEMISTRY | 2011年 / 11卷 / 21期
关键词：
Metallodrugs; platinum; biomolecules binding; P-ISOPROPYLBENZALDEHYDE THIOSEMICARBAZONE; ISATIN-BETA-THIOSEMICARBAZONES; INTERSTRAND CROSS-LINKS; CELL-CYCLE PROGRESSION; CYTOTOXIC ACTIVITY; IN-VITRO; TUMOR-CELLS; COORDINATION-COMPLEXES; ANTICANCER COMPLEXES; APOPTOSIS INDUCTION;
D O I：
10.2174/156802611798040723
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The potential and limitations of the non classical metallodrugs with platinum as metal are discussed in this section, focusing not only in their design but in their mechanism of action and interaction with other biomolecules to introduce and encourage the readers on the potential of this field.
引用
收藏
页码：2613 / 2622
页数：10
相关论文
共 50 条
  • [1] Progress in non-classical antitumor platinum drugs
    Wang, LH
    Liu, Y
    You, QD
    Gou, SH
    PROGRESS IN CHEMISTRY, 2004, 16 (03) : 456 - 462
  • [2] Anticancer platinum-based complexes with non-classical structures
    Cai, Linxiang
    Yu, Congtao
    Ba, Linkui
    Liu, Qinghua
    Qian, Yunxu
    Yang, Bo
    Gao, Chuanzhu
    APPLIED ORGANOMETALLIC CHEMISTRY, 2018, 32 (04)
  • [3] SALICYLATE AND CATECHOLATE PLATINUM COMPLEXES - NEW POTENTIAL ANTITUMOR DRUGS
    SCHWARTZ, P
    GALE, GR
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1986, 192 : 133 - INOR
  • [4] Potential use of non-classical pathways for the transport of macromolecular drugs
    Kueltzo, LA
    Middaugh, CR
    EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2000, 9 (09) : 2039 - 2050
  • [5] On the potential of non-classical constituency
    Haselager, WFG
    CONNECTIONISM AND THE PHILOSOPHY OF PSYCHOLOGY, 1999, 22 : 23 - 42
  • [6] Non-classical divalent lanthanide complexes
    Nief, Francois
    DALTON TRANSACTIONS, 2010, 39 (29) : 6589 - 6598
  • [7] Current development in antitumor platinum complexes
    Guo, JX
    Sun, SX
    Wang, HC
    CHINESE JOURNAL OF INORGANIC CHEMISTRY, 2002, 18 (02) : 125 - 129
  • [8] Structures and microstructures of non-classical pyriboles
    Bozhilov, Krassimir N.
    MINERALS AT THE NANOSCALE, 2013, 14 : 109 - 152
  • [9] Understanding trans platinum complexes as potential antitumor drugs beyond targeting DNA
    Quiroga, A. G.
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2012, 114 : 106 - 112
  • [10] NON-CLASSICAL THERMAL INJECTION CURRENT IN GAP P-N STRUCTURES
    EVSTROPOV, VV
    KALININ, BN
    TSARENKOV, BV
    SOVIET PHYSICS SEMICONDUCTORS-USSR, 1983, 17 (04): : 373 - 378
12345