Simple method for the synthesis of 1-substituted β-carboline derivatives from tryptamine and carboxylic acids in polyphosphoric acid

被引：19
|
作者：
Ivanov, I [1 ]
Nikolova, S [1 ]
Statkova-Abeghe, S [1 ]
机构：
[1] Paisij Hilendarski Univ Plovdiv, Dept Organ Chem, BG-4000 Plovdiv, Bulgaria
来源：
HETEROCYCLES | 2005年 / 65卷 / 10期
关键词：
D O I：
10.3987/COM-05-10484
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A number of 1-substituted 3,4-dihydro-9H-beta-carboline derivatives (4) with high purity and yields have been synthesized by treating of tryptamine (1) with carboxylic acids (2) in polyphosphoric acid. 3,4-Dihydro-9H-beta-carbolines (4) were successfully transformed to 1,2,3,4-tetrahydro-9H-beta-carbolines (5) and 9H-beta-carbolines (6).
引用
收藏
页码：2483 / 2492
页数：10
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