Mediator complex components are frequent targets for genetic alterations in various types of human cancer

被引:1
|
作者
Deng, Libin [1 ,2 ]
Zhang, Cheng [3 ]
Miao, Duling [1 ]
Tang, Xiaoli [2 ]
Luo, Shiwen [2 ,3 ]
Xin, Hong-Bo [1 ]
Shi, Huidong [4 ,5 ]
机构
[1] Nanchang Univ, Inst Translat Med, Nanchang 330031, Jiangxi, Peoples R China
[2] Nanchang Univ, Med Sch, Nanchang 330031, Jiangxi, Peoples R China
[3] Nanchang Univ, Affiliated Hosp 1, Ctr Med Expt, Nanchang 330006, Jiangxi, Peoples R China
[4] Augusta Univ, Med Coll Georgia, Dept Biochem & Mol Biol, Augusta, GA 30912 USA
[5] Augusta Univ, Georgia Canc Ctr, Augusta, GA 30912 USA
基金
中国国家自然科学基金; 美国国家卫生研究院;
关键词
MED12; MUTATIONS; UTERINE LEIOMYOMAS; ENHANCER; TRANSCRIPTION; INHIBITION;
D O I
10.1016/j.jgg.2017.08.006
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:587 / 591
页数:5
相关论文
共 50 条
  • [1] Mediator complex components are frequent targets for genetic alterations in various types of human cancer
    Libin Deng
    Cheng Zhang
    Duling Miao
    Xiaoli Tang
    Shiwen Luo
    Hong-Bo Xin
    Huidong Shi
    Journal of Genetics and Genomics, 2017, 44 (12) : 587 - 591
  • [2] Comprehensive analysis of the transcriptional profile of the Mediator complex across human cancer types
    Syring, Isabella
    Kluemper, Niklas
    Offermann, Anne
    Braun, Martin
    Deng, Mario
    Boehm, Diana
    Queisser, Angela
    von Maessenhausen, Anne
    Braegelmann, Johannes
    Vogel, Wenzel
    Schmidt, Doris
    Majores, Michael
    Schindler, Anne
    Kristiansen, Glen
    Mueller, Stefan C.
    Ellinger, Joerg
    Shaikhibrahim, Zaki
    Perner, Sven
    ONCOTARGET, 2016, 7 (17) : 23043 - 23055
  • [3] Large-scale phenogenomic analysis of human cancers uncovers frequent alterations affecting SMC5/6 complex components in breast cancer
    Roy, Shamayita
    Zaker, Arvin
    Mer, Arvind
    D'Amours, Damien
    NAR CANCER, 2023, 5 (03):
  • [4] Detection of genetic alterations in human cancer
    Shimizu, K
    SEIKAGAKU, 1997, 69 (05): : 311 - 323
  • [5] Genetic alterations in human pancreatic cancer
    Horii, A
    Kimura, M
    Abe, T
    Fukushige, S
    Furukawa, T
    Sunamura, M
    Kobari, M
    Matsuno, S
    RECENT ADVANCES IN GASTROENTEROLOGICAL CARCINOGENESIS I, 1996, : 231 - 238
  • [6] Contribution of cell types and genetic alterations in breast cancer progression
    Bhagirath, Divya
    Zhao, Xiangshan
    West, William W.
    Band, Hamid
    Band, Vimla
    CANCER RESEARCH, 2015, 75
  • [7] GENETIC ALTERATIONS IN HUMAN GASTRIC-CANCER
    HIROHASHI, S
    SUGIMURA, T
    CANCER CELLS-A MONTHLY REVIEW, 1991, 3 (02): : 49 - 52
  • [8] Double strand break repair components are frequent targets of microsatellite instability in endometrial cancer
    Bilbao, Cristina
    Ramirez, Raquel
    Rodriguez, German
    Falcon, Orlando
    Leon, Laureano
    Diaz-Chico, Nicolas
    Perucho, Manuel
    Carlos Diaz-Chico, Juan
    EUROPEAN JOURNAL OF CANCER, 2010, 46 (15) : 2821 - 2827
  • [9] Multiple genetic alterations cause frequent and heterogeneous human histocompatibility leukocyte antigen class I loss in cervical cancer
    Koopman, LA
    Corver, WE
    van der Slik, AR
    Giphart, MJ
    Fleuren, GJ
    JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 191 (06): : 961 - 975
  • [10] FREQUENT ALTERATIONS OF SPECIFIC REITERATED DNA-SEQUENCE ABUNDANCES IN HUMAN CANCER
    BASKIN, F
    GROSSMAN, A
    BHAGAT, SG
    BURNS, D
    DAVIS, RM
    WARMOTH, LA
    ROSENBERG, RN
    CANCER GENETICS AND CYTOGENETICS, 1987, 28 (01) : 163 - 172