The antioxidative effect of the bacteria Dienococcus radiophilus against LDL lipid peroxidation

被引：5
|
作者：
Lavy, A [1 ]
Neeman, Y [1 ]
Fuhrman, B [1 ]
机构：
[1] Technion Israel Inst Technol, Fac Med, Rappaport Family Inst Res Med Sci, Bnai Zion Med Ctr,Lipid Res Lab, IL-31048 Haifa, Israel
来源：
EUROPEAN JOURNAL OF NUTRITION | 2005年 / 44卷 / 05期
关键词：
antioxidants; lipid peroxidation; bacteria;
D O I：
10.1007/s00394-004-0522-y
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Background Lipid peroxidation is an important process in the development of atherosclerosis. Thus agents with antioxidant properties may play an important role in the inhibition of atherosclerosis. Objectives In this study we aimed to show that the lipid extract of the bacteria Deinococcus radiophilus (leDR) has antioxidant properties against LDL oxidation. Results This antioxidant effect was shown in both transition metal ion and free radical generating systems. We also showed that leDR can protect LDL from UV light-induced oxidative damage. The antioxidative capacity of leDR is partly due to copper ion chelation. Conclusion We conclude that some specific bacteria constituent has the ability to inhibit LDL oxidation and, thus, to attenuate atherogenesis.
引用
收藏
页码：281 / 284
页数：4
相关论文
共 50 条
  • [1] The antioxidative effect of the bacteria Dienococcus radiophilus against LDL lipid peroxidation
    A. Lavy
    Y. Neeman
    B. Fuhrman
    European Journal of Nutrition, 2005, 44 : 281 - 284
  • [2] The antioxidative effect of ganhuangenin against lipid peroxidation
    Lim, BO
    Yu, BP
    Kim, SC
    Park, DK
    PHYTOTHERAPY RESEARCH, 1999, 13 (06) : 479 - 483
  • [3] Studies on antioxidative mechanisms of catechins against lipid peroxidation
    Kondo, K
    Kurihara, M
    Suzuki, T
    Miyata, N
    Toyoda, M
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1998, 215 : U885 - U886
  • [4] Antioxidative effect of sesamol and related compounds on lipid peroxidation
    Uchida, M
    Nakajin, S
    Toyoshima, S
    Shinoda, M
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 1996, 19 (04) : 623 - 626
  • [5] ANTIOXIDATIVE EFFECT OF HUMAN SALIVA ON LIPID-PEROXIDATION
    TERAO, J
    NAGAO, A
    AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1991, 55 (03): : 869 - 872
  • [6] LDL-associated phospholipase A does not protect LDL against lipid peroxidation in vitro
    Schnitzer, E
    Pinchuk, I
    Fainaru, M
    Lichtenberg, D
    Yedgar, S
    FREE RADICAL BIOLOGY AND MEDICINE, 1998, 24 (7-8) : 1294 - 1303
  • [7] Synthesis of lipophilic clovamide derivatives and their antioxidative potential against lipid peroxidation
    Ley, JP
    Bertram, HJ
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2003, 51 (16) : 4596 - 4602
  • [8] Effect of ethylene glycol on antioxidative enzymes and lipid peroxidation in erythrocytes
    Jurczyk, AP
    Galecki, P
    Berent, J
    Kedziora, J
    Jankowska, B
    Fijalkowski, P
    Blaszczyk, J
    Meissner, E
    Szram, S
    16TH MEETING OF THE INTERNATIONAL ASSOCIATION OF FORENSIC SCIENCES, 2002, : 257 - 260
  • [9] The effect of drought on activity of some antioxidative enzymes and lipid peroxidation
    Valentovic, P
    Luxová, M
    Takác, T
    BIOLOGIA, 2004, 59 : 201 - 204
  • [10] ANTIOXIDATIVE EFFECT OF MAMMALIAN LIVER HYDROLYZATE ON LIPID-PEROXIDATION
    AIMOTO, T
    HIRATA, M
    HIRAKI, Y
    DOTE, C
    INOUE, N
    IMAI, K
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1994, 114 (02): : 89 - 93
12345