Stereo-effect of the peptide formation reaction by N-(O,O-diisopropyl) phosphoryl serine

被引：0
|
作者：
Hu, JJ [1 ]
Ju, Y [1 ]
Zhao, YF [1 ]
机构：
[1] Tsing Hua Univ, Sch Life Sci & Engn, Dept Chem, Key Lab Bioorgan Phosphorus Chem Educ Minist, Beijing 100084, Peoples R China
来源：
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE | 2001年 / 22卷 / 03期
关键词：
chirality; N-(O; O-diisopropyl) phosphoryl serine; ion-paired RP-HPLC; serylhistidine; stereoselectivity;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The reactions between N-phosphoryl-L- (or D-) serine and L- (or D-) histidine or L- (or D-) histidine methyl ester were investigated. Products of the reaction mixtures were analyzed by ion-pair reversed-phase HPLC with SDS as the ion-pairing reagent. The results showed that dipeptide serylhistidine was formed in all these reaction systems, and L-L and D-D types of serylhistidine were yielded in an amount about four times as much as that of the L-D and D-L type dipeptide.
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页码：399 / 402
页数：4
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