Framework for real-time peptide-mapping (RT-PM) in bioreactor cultures of recombinant protein producing CHO cells

被引：0
|
作者：
Tharmalingam, Tharmala [1 ]
Wu, Chao-Hsiang [1 ]
Hong, Robert [1 ]
Benchaar, Sabrina [1 ]
Goudar, Chetan [1 ]
机构：
[1] Amgen Inc, Thousand Oaks, CA 91320 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2015年 / 249卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
147
引用
收藏
页数：1
相关论文
共 10 条
  • [1] Real-time monitoring of the physiological state of CHO cells in bioreactor by using a dual spectroscopic strategy
    Franck Courtès
    Bruno Ebel
    Emmanuel Guedon
    Annie Marc
    BMC Proceedings, 9 (Suppl 9)
  • [2] Real-Time Monitoring of Antibody Glycosylation Site Occupancy by In Situ Raman Spectroscopy During Bioreactor CHO Cell Cultures
    Li, Meng-Yao
    Ebel, Bruno
    Paris, Cedric
    Chauchard, Fabien
    Guedon, Emmanuel
    Marc, Annie
    BIOTECHNOLOGY PROGRESS, 2018, 34 (02) : 486 - 493
  • [3] Control of IgG glycosylation by in situ and real-time estimation of specific growth rate of CHO cells cultured in bioreactor
    Li, Meng-Yao
    Ebel, Bruno
    Blanchard, Fabrice
    Paris, Cedric
    Guedon, Emmanuel
    Marc, Annie
    BIOTECHNOLOGY AND BIOENGINEERING, 2019, 116 (05) : 985 - 993
  • [4] Real-time monitoring of recombinant protein concentration in animal cell cultures using an optical biosensor
    Baker, K
    Ison, A
    Freedman, R
    Jones, W
    James, D
    GENETIC ENGINEER AND BIOTECHNOLOGIST, 1997, 17 (2-3): : 69 - 74
  • [5] Parallel comparison of in situ Raman and NIR spectroscopies to simultaneously measure multiple variables toward real-time monitoring of CHO cell bioreactor cultures
    Li, Mengyao
    Ebel, Bruno
    Chauchard, Fabien
    Guedon, Emmanuel
    Marc, Annie
    BIOCHEMICAL ENGINEERING JOURNAL, 2018, 137 : 205 - 213
  • [6] Exploring Physical and Chemical Factors Influencing the Properties of Recombinant Prion Protein and the Real-Time Quaking-Induced Conversion (RT-QuIC) Assay
    Cheng, Keding
    Sloan, Angela
    Avery, Kristen M.
    Coulthart, Michael
    Carpenter, Michael
    Knox, J. David
    PLOS ONE, 2014, 9 (01):
  • [7] Monitoring Protein-Ligand Interactions in Human Cells by Real-Time Quantitative In-Cell NMR using a High Cell Density Bioreactor
    Barbieri, Letizia
    Luchinat, Enrico
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2021, (169):
  • [8] Real-time RT-PCR quantification of pregnancy-associated plasma protein-A mRNA abundance in bovine granulosa and theca cells: Effects of hormones in vitro
    Aad, Pauline Y.
    Voge, Justin L.
    Santiago, Consuelo A.
    Malayer, Jerry R.
    Spicer, Leon J.
    DOMESTIC ANIMAL ENDOCRINOLOGY, 2006, 31 (04) : 357 - 372
  • [9] Real-time monitoring of β-amyloid peptide-induced apoptosis in SH-SY5Y neuroblastoma cells expressing a GFP-tagged nuclear pore protein
    Holmlund, L
    Beckman, M
    Imreh, G
    Hallberg, E
    Iverfeldt, K
    JOURNAL OF NEUROCHEMISTRY, 2001, 78 : 138 - 138
  • [10] Up-regulation of vimentin, ribosomal protein L6 (RPL6) and type IPTH receptor (PTH1R) genes by intermittent PTH treatment in MC3T3-E1 osteoblast-like cells: Use of real-time RT-PCR in combination with genearray analysis.
    Iida-Klein, A
    Lu, SS
    Bischoff, D
    Yamaguchi, DT
    Lindsay, R
    JOURNAL OF BONE AND MINERAL RESEARCH, 2003, 18 : S109 - S109
1