The significance of environmental exposure on the progression of allergic diseases

被引：5
|
作者：
Wahn, U. [1 ]
机构：
[1] Charite, Dept Paediat Pneumol & Immunol, Berlin, Germany
来源：
ALLERGY | 2011年 / 66卷
关键词：
environmental risk factors; genetic predisposition; the allergic march; tolerance induction; 1ST; 3; YEARS; INHALANT ALLERGENS; ATOPIC-DERMATITIS; SENSITIZATION; LIFE; RISK; CHILDREN; BIRTH; FOOD;
D O I：
10.1111/j.1398-9995.2011.02621.x
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
P>In addition to strong genetic influences on atopic sensitization and disease development in infancy and childhood, a number of environmental factors modulate clinical and immunological phenotypes early in life and even prenatally. These factors include gastrointestinal or skin exposure to food allergens; respiratory exposure to indoor and outdoor allergens; presence of environmental pollutants such as tobacco smoke; and exposure to microbial compounds.
引用
收藏
页码：7 / 9
页数：3
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