Fe(iii)-catalysed selective C-N bond cleavage of N-phenylamides by an electrochemical method

被引：3

作者：

Xu, Yiwen ^{[1
]}

Long, Yang ^{[1
]}

Ye, Runyou ^{[1
]}

Li, Qiang ^{[1
]}

Ke, Fang ^{[2
]}

Zhou, Xiangge ^{[1
]}

机构：

[1] Sichuan Univ, Coll Chem, Wangjiang Rd 29, Chengdu 610064, Peoples R China

[2] Fujian Med Univ, Sch Pharm, Fujian Prov Key Lab Nat Med Pharmacol, Fuzhou 350004, Peoples R China

来源：

RSC ADVANCES | 2022年 / 12卷 / 37期

基金：

中国国家自然科学基金;

关键词：

H ACTIVATION; AMIDES; BENZOXAZOLES; KETONES; REAGENTS;

D O I：

10.1039/d2ra04709h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An Fe(iii)-catalysed transformation of secondary N-phenyl substituted amides to primary amides by an electrochemical method is developed. Regioselective aryl C-H oxygenation occurs during the reaction, promoting selective C(phenyl)-N bond cleavage to form primary amides in yields of up to 92%.

引用

页码：24217 / 24221

页数：5

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