RNA polymerase: Structural similarities between bacterial RNA polymerase and eukaryotic RNA polymerase II

被引：184

作者：

Ebright, RH ^{[1
]}

机构：

[1] Rutgers State Univ, Howard Hughes Med Inst, Piscataway, NJ 08854 USA

[2] Rutgers State Univ, Waksman Inst, Piscataway, NJ 08854 USA

[3] Rutgers State Univ, Dept Chem, Piscataway, NJ 08854 USA

来源：

JOURNAL OF MOLECULAR BIOLOGY | 2000年 / 304卷 / 05期

关键词：

RNA polymerase; RNA polymerase II; open complex; elongation complex; transcription;

D O I：

10.1006/jmbi.2000.4309

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bacterial RNA polymerase and eukaryotic RNA polymerase II exhibit striking structural similarities, including similarities in overall structure, relative positions of subunits, relative positions of functional determinants, and structures and folding topologies of subunits. These structural similarities are paralleled by similarities in mechanisms of interaction with DNA. (C) 2000 Academic Press.

引用

页码：687 / 698

页数：12

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