The role of angiogenesis in the spread of oral squamous cell carcinoma

被引：52
|
作者：
Penfold, CN
Partridge, M
Rojas, R
Langdon, JD
机构：
[1] UNIV LONDON KINGS COLL HOSP,MAXILLOFACIAL UNIT,LONDON SE5 9RW,ENGLAND
[2] UNIV LONDON KINGS COLL,SCH MED & DENT,EPITHELIAL CELL BIOL UNIT,DEPT ORAL & MAXILLOFACIAL SURG,LONDON SE5 9RW,ENGLAND
来源：
BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY | 1996年 / 34卷 / 01期
关键词：
D O I：
10.1016/S0266-4356(96)90133-3
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Microvessels were counted in 41 primary oral squamous cell carcinomas using JC70 antibody to PECAM (CD31). The counts were compared with clinical and pathological indicators of tumour behaviour including lymph node status, tumour stage, type of histological differentiation, size and velocity of tumour growth. Tumour microvessel counts correlated with lymph node metastasis (p < 0.001). This association was independent of tumour size, velocity and type of histological differentiation and when all the variables were analysed by multivariate analysis only vascular count showed a significant association with lymph node metastasis.
引用
收藏
页码：37 / 41
页数：5
相关论文
共 50 条
  • [1] The role of mast cells on angiogenesis in oral squamous cell carcinoma
    Kalra, Manpreet
    Rao, Nirmala
    Nanda, Kanwardeep
    Rehman, Farzan
    Girish, K. L.
    Tippu, Shoaib
    Arora, Asit
    [J]. MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL, 2012, 17 (02): : E190 - E196
  • [2] Pivotal Role of Angiogenesis in Oral Squamous Cell Carcinoma: A Review
    Rohit, Jaiswal
    Manjunath, Badni
    [J]. JOURNAL OF ADVANCED ORAL RESEARCH, 2011, 2 (03) : 1 - 4
  • [3] EXTRACAPSULAR SPREAD IN ORAL SQUAMOUS CELL CARCINOMA
    Shaw, Richard J.
    Lowe, Derek
    Woolgar, Julia A.
    Brown, James S.
    Vaughan, E. David
    Evans, Christopher
    Lewis-Jones, Huw
    Hanlon, Rebecca
    Hall, Gillian L.
    Rogers, Simon N.
    [J]. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2010, 32 (06): : 714 - 722
  • [4] Role of angiogenesis in oral squamous cell carcinoma development and metastasis: an immunohistochemical study
    Shivamallappa, Shivakumar Madappa
    Venkatraman, Narayan Tondikulam
    Shreedhar, Balasundari
    Mohanty, Leeky
    Shenoy, Sadhana
    [J]. INTERNATIONAL JOURNAL OF ORAL SCIENCE, 2011, 3 (04) : 216 - 224
  • [5] Role of angiogenesis in oral squamous cell carcinoma development and metastasis: an immunohistochemical study
    Shivakumar Madappa Shivamallappa
    Narayan Tondikulam Venkatraman
    Balasundari Shreedhar
    Leeky Mohanty
    Sadhana Shenoy
    [J]. International Journal of Oral Science, 2011, 3 : 216 - 224
  • [6] Role of angiogenesis in oral squamous cell carcinoma development and metastasis: an immunohistochemical study
    Shivakumar Madappa Shivamallappa
    Narayan Tondikulam Venkatraman
    Balasundari Shreedhar
    Leeky Mohanty
    Sadhana Shenoy
    [J]. International Journal of Oral Science, 2011, (04) : 216 - 224
  • [7] Role of angiogenesis in oral squamous cell carcinoma development and metastasis: an immunohistochemical study
    Shivakumar Madappa Shivamallappa
    Narayan Tondikulam Venkatraman
    Balasundari Shreedhar
    Leeky Mohanty
    Sadhana Shenoy
    [J]. International Journal of Oral Science., 2011, 3 (04) - 224
  • [8] Neutrophils regulate tumor angiogenesis in oral squamous cell carcinoma and the role of Chemerin
    Gao, Fei
    Feng, Yuanyong
    Hu, Xiaoyuan
    Zhang, Xuan
    Li, Tongtong
    Wang, Yueqi
    Ge, Shengyou
    Wang, Chengqin
    Chi, Jinghua
    Tan, Xiaohua
    Wang, Ning
    [J]. INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 121
  • [9] The role of mast cells and angiogenesis in well-differentiated oral squamous cell carcinoma
    Tahir, Ali
    Nagi, Abdul Hannan
    Ullah, Ehsan
    Janjua, Omer Sefvan
    [J]. JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 2013, 9 (03) : 387 - 391
  • [10] Immunohistochemical evaluation of tumor angiogenesis and the role of mast cells in oral squamous cell carcinoma
    Kabiraj, Arpita
    Jaiswal, Rohit
    Singh, Anil
    Gupta, Jagriti
    Singh, Arun
    Samadi, Fahad M.
    [J]. JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 2018, 14 (03) : 495 - 502
12345