New rapid antigen test for diagnosis of pneumococcal meningitis
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作者:
Marcos, MA
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Hosp Clin Univ, Inst Invest Biomed August Pi & Sunyer, Microbiol Unit, Barcelona, SpainHosp Clin Univ, Inst Invest Biomed August Pi & Sunyer, Microbiol Unit, Barcelona, Spain
Marcos, MA
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Martínez, E
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机构:Hosp Clin Univ, Inst Invest Biomed August Pi & Sunyer, Microbiol Unit, Barcelona, Spain
Martínez, E
Almela, M
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机构:Hosp Clin Univ, Inst Invest Biomed August Pi & Sunyer, Microbiol Unit, Barcelona, Spain
Almela, M
Mensa, J
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机构:Hosp Clin Univ, Inst Invest Biomed August Pi & Sunyer, Microbiol Unit, Barcelona, Spain
Mensa, J
de Anta, MTJ
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机构:Hosp Clin Univ, Inst Invest Biomed August Pi & Sunyer, Microbiol Unit, Barcelona, Spain
de Anta, MTJ
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[1] Hosp Clin Univ, Inst Invest Biomed August Pi & Sunyer, Microbiol Unit, Barcelona, Spain
[2] Hosp Clin Univ, Inst Invest Biomed August Pi & Sunyer, Infect Dis Unit, Barcelona, Spain
[3] Hosp Clin Univ, Inst Invest Biomed August Pi & Sunyer, Clin Inst Infect & Immunol, Barcelona, Spain
Conventional diagnostic methods for bacterial meningitis are frequently not rapid or sensitive enough to guide initial antimicrobial therapy. Streptococcus pneumoniae is the most frequent and severe cause of community-acquired bacterial meningitis and treatment is complicated by the Increasing prevalence of antimicrobial resistance to third-generation cephalosporins. We used a new rapid antigen test in the cerebrospinal fluid and urine of patients with suspected bacterial meningitis, and found It to be highly sensitive and specific for the detection of pneumococci. This test might help guide Initial therapy for bacterial meningitis according to the local rates of pneumococcal antimicrobial resistance.
机构:
Univ Cape Town, Fac Hlth Sci, Div Med Microbiol, Cape Town, South Africa
Groote Schuur Hosp, Natl Hlth Lab Serv, Microbiol, Cape Town, South AfricaUniv Cape Town, Fac Hlth Sci, Div Med Microbiol, Cape Town, South Africa
Tootla, Hafsah D.
Bamford, Colleen
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Univ Cape Town, Fac Hlth Sci, Div Med Microbiol, Cape Town, South Africa
Groote Schuur Hosp, Natl Hlth Lab Serv, Microbiol, Cape Town, South AfricaUniv Cape Town, Fac Hlth Sci, Div Med Microbiol, Cape Town, South Africa
Bamford, Colleen
Centner, Chad M.
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Univ Cape Town, Fac Hlth Sci, Div Med Microbiol, Cape Town, South Africa
Groote Schuur Hosp, Natl Hlth Lab Serv, Microbiol, Cape Town, South AfricaUniv Cape Town, Fac Hlth Sci, Div Med Microbiol, Cape Town, South Africa
Centner, Chad M.
Moodley, Clinton
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Univ Cape Town, Fac Hlth Sci, Div Med Microbiol, Cape Town, South Africa
Groote Schuur Hosp, Natl Hlth Lab Serv, Microbiol, Cape Town, South AfricaUniv Cape Town, Fac Hlth Sci, Div Med Microbiol, Cape Town, South Africa
机构:Catholic Univ Lille, Fac Med, St Philibert Hosp, Microbiol Lab, F-59462 Lomme Les Lille, France
Charkaluk, Marie-Laure
Kalach, Nicolas
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机构:Catholic Univ Lille, Fac Med, St Philibert Hosp, Microbiol Lab, F-59462 Lomme Les Lille, France
Kalach, Nicolas
Mvogo, Hector
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机构:Catholic Univ Lille, Fac Med, St Philibert Hosp, Microbiol Lab, F-59462 Lomme Les Lille, France
Mvogo, Hector
Dehecq, Eric
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机构:Catholic Univ Lille, Fac Med, St Philibert Hosp, Microbiol Lab, F-59462 Lomme Les Lille, France
Dehecq, Eric
Magentie, Helene
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机构:Catholic Univ Lille, Fac Med, St Philibert Hosp, Microbiol Lab, F-59462 Lomme Les Lille, France
Magentie, Helene
Raymond, Josette
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机构:Catholic Univ Lille, Fac Med, St Philibert Hosp, Microbiol Lab, F-59462 Lomme Les Lille, France
Raymond, Josette
Gendrel, Dorninique
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机构:Catholic Univ Lille, Fac Med, St Philibert Hosp, Microbiol Lab, F-59462 Lomme Les Lille, France
Gendrel, Dorninique
Kremp, Odile
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机构:Catholic Univ Lille, Fac Med, St Philibert Hosp, Microbiol Lab, F-59462 Lomme Les Lille, France
Kremp, Odile
Decoster, Anne
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Catholic Univ Lille, Fac Med, St Philibert Hosp, Microbiol Lab, F-59462 Lomme Les Lille, FranceCatholic Univ Lille, Fac Med, St Philibert Hosp, Microbiol Lab, F-59462 Lomme Les Lille, France