Effectiveness and cost-effectiveness of influenza vaccination for elderly people

被引：2

作者：

Sugishita, Yoshiyuki ^{[1
]}

Sugawara, Tamie ^{[1
]}

机构：

[1] Natl Inst Infect Dis, Tokyo, Japan

来源：

VACCINE | 2021年 / 39卷 / 52期

关键词：

TEST-NEGATIVE DESIGN; SEASONAL INFLUENZA; ANTIBODY-RESPONSE; IMMUNE-RESPONSE; ADULTS; VACCINES; PROGRAM; QUADRIVALENT; POPULATION; EFFICACY;

D O I：

10.1016/j.vaccine.2021.09.054

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

For elderly people who have low incidence of influenza, calculation of credible vaccine effectiveness (VE) sometimes becomes difficult. Currently, VE for elderly people is insufficient to ascertain the precise efficacy specifically. Cost-effectiveness of influenza vaccination of elderly people is discussed widely in terms of topics and areas. This report describes research results demonstrating influenza vaccination effectiveness among elderly people based on recent findings. Newly available influenza vaccination for elderly people appears to be cost-effective compared with that of trivalent inactiveted influenza vaccine. Overall, for all influenza virus types, it remains unclear whether influenza vaccination shows high VE. A decreasing effect of repeated vaccination was confirmed partially by test negative design and a serological study of cohorts. However, some studies have found no such decreasing effect. Measurement of VE and subsequent analysis of the cost-effectiveness of influenza vaccination for elderly people requires long-term monitoring using serological studies and test negative design. (C) 2021 Elsevier Ltd. All rights reserved.

引用

页码：7531 / 7540

页数：10

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