Selecting Informative Genes from Microarray Data by Using a Cyclic GA-based Method

被引:0
|
作者
Mohamad, Mohd Saberi [1 ,2 ]
Omatu, Sigeru [1 ]
Deris, Safaai [2 ]
Yoshioka, Michifumi [1 ]
机构
[1] Osaka Prefecture Univ, Dept Comp Sci & Intelligent Syst, Osaka 5998531, Japan
[2] Univ Teknol Malaysia, Dept Software Engn, Skudai 81310, Johore, Malaysia
关键词
component; Cyclic approach; Genetic algorithms; Gene selection; hybrid method; microarray data; SUPPORT VECTOR MACHINE; CLASSIFICATION; ALGORITHM; HYBRID;
D O I
暂无
中图分类号
TP301 [理论、方法];
学科分类号
081202 ;
摘要
Microarray data are expected to be of significant help in the development of efficient cancer diagnoses and classification platforms. The main problem that needs to be addressed is the selection of a small subset of genes from the thousands of genes in the data that contributes to a cancer disease. This selection process is difficult due to the availability of a small number of samples compared to the huge number of genes, many irrelevant genes, and noisy genes. Therefore, this paper proposes a cyclic method based on genetic algorithms (GA) to select a near-optimal (small) subset of informative genes that is relevant for cancer classification. The performance of the proposed method was evaluated by three benchmark microarray data sets and obtained encouraging results as compared with other experimented methods and previous related works.
引用
收藏
页码:15 / +
页数:2
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