Protein annotation and modelling servers at University College London

被引：281

作者：

Buchan, D. W. A. ^{[1
]}

Ward, S. M. ^{[1
]}

Lobley, A. E. ^{[1
]}

Nugent, T. C. O. ^{[1
]}

Bryson, K. ^{[1
]}

Jones, D. T. ^{[1
]}

机构：

[1] UCL, Bioinformat Grp, London WC1E 6BT, England

来源：

NUCLEIC ACIDS RESEARCH | 2010年 / 38卷

基金：

英国生物技术与生命科学研究理事会;

关键词：

PREDICTION; DATABASE;

D O I：

10.1093/nar/gkq427

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The UCL Bioinformatics Group web portal offers several high quality protein structure prediction and function annotation algorithms including PSIPRED, pGenTHREADER, pDomTHREADER, MEMSAT, MetSite, DISOPRED2, DomPred and FFPred for the prediction of secondary structure, protein fold, protein structural domain, transmembrane helix topology, metal binding sites, regions of protein disorder, protein domain boundaries and protein function, respectively. We also now offer a fully automated 3D modelling pipeline: BioSerf, which performed well in CASP8 and uses a fragment-assembly approach which placed it in the top five servers in the de novo modelling category. The servers are available via the group web site at http://bioinf.cs.ucl.ac.uk/.

引用

页码：W563 / W568

页数：6

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