One hundred years of Drosophila cancer research: no longer in solitude

被引：28
|
作者：
Villegas, Santiago Nahuel [1 ,2 ]
机构：
[1] CSIC, Inst Neurociencias, Campus St Joan,Apartado 18, Alicante 03550, Spain
[2] UMH, Campus St Joan,Apartado 18, Alicante 03550, Spain
来源：
DISEASE MODELS & MECHANISMS | 2019年 / 12卷 / 04期
关键词：
Cancer; Drosophila; Mary Stark; Metastasis; TUMOR-GROWTH; MALIGNANT-TUMORS; ASYMMETRIC DIVISION; POPULATION-DENSITY; CHROMOSOME THEORY; GENETIC MOSAICS; CELL POLARITY; BENIGN-TUMOR; MELANOGASTER; HEREDITARY;
D O I：
10.1242/dmm.039032
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
When Mary Stark first described the presence of tumours in the fruit fly Drosophila melanogaster in 1918, would she ever have imagined that flies would become an invaluable organism for modelling and understanding oncogenesis? And if so, would she have expected it to take 100 years for this model to be fully accredited? This Special Article summarises the efforts and achievements of Drosophilists to establish the fly as a valid model in cancer research through different scientific periods.
引用
收藏
页数：5
相关论文
共 50 条
12345