Allograft Bone What Is the Role of Platelet-Derived Growth Factor in Hindfoot and Ankle Fusions

被引：5

作者：

Scott, Ryan T. ^{[1
]}

McAlister, Jeffrey E. ^{[1
]}

Rigby, Ryan B. ^{[2
]}

机构：

[1] CORE Inst, 18444 North 25th Ave,Suite 210, Phoenix, AZ 85023 USA

[2] Logan Reg Orthoped, 1350 North 500 East, Logan, UT 84341 USA

来源：

CLINICS IN PODIATRIC MEDICINE AND SURGERY | 2018年 / 35卷 / 01期

关键词：

Platelet-derived growth factor; PDGF; Ankle; Hindfoot; Fusion; Bone graft; Allograft; MESENCHYMAL STEM-CELLS; FACTOR-BB; RHPDGF-BB; ILIAC CREST; PDGF-BB; FOOT; GRAFT; MIGRATION; BETA; PROLIFERATION;

D O I：

10.1016/j.cpm.2017.08.008

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Arthrodesis of the ankle or foot is a common procedure for chronic pain and disability. Nonunion remains a prevalent complication among arthrodesis procedures. Some patients present with an inherent risk of developing a nonunion. Allograft biologics have gained popularity in an effort to reduce complications such as nonunion. Various biologics bring unique properties while maintaining a singular purpose. Platelet-derived growth factor (PDGF) may be introduced into a fusion site to facilitate healthy bony consolidation. The purpose of this article was to review the benefits and modalities of PDGF and how it can improve patient outcomes in ankle and hindfoot fusions.

引用

页码：37 / +

页数：17

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